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Bioenergy
RIBOSE™ and Heart Health
Scientific and clinical
studies have repeatedly shown that Bioenergy RIBOSE can restore energy
and improve function in ischemic, hypoxic, and failing hearts. Oxygen
deprivation causes hearts to use energy faster than it can be replaced
through normal processes of tissue energy turnover. The result is a
depletion of cellular energy reserves translating to loss of heart
function.
Millions of Americans suffer the affects of coronary artery disease, and
the prevalence of congestive heart failure is reaching epidemic
proportions. Recent research has also proven that high-intensity
endurance exercise places a considerable strain on the heart, leading to
a loss of diastolic heart function that persists for several weeks to
months following an event. Other research, conducted at the Mayo Clinic
and published in the Journal of the American Medical Association, showed
that and average of 26% of the population, male and female, have
symptoms of cardiac diastolic dysfunction. More than half of those
affected are unaware of their condition, but all are at risk for
developing congestive heart failure.
When hearts lose energy, they first suffer a loss of diastolic function.
The diastolic phase of the heartbeat is the relaxation phase, during
which the heart fills with blood for the next heartbeat. A loss of
diastolic capacity means less blood will circulate to the body during
each beat, and frequently leads to a thickening and expansion of the
heart muscle, known as hypertrophy. The result of chronic diastolic
dysfunction can be congestive heart failure. For patients, the
progressive consequence of the disease is shortness of breath, loss of
exercise capacity, overwhelming fatigue, and worse.
Bioenergy RIBOSE increases cardiac energy to help fuel the heart. For
patients, this can mean more energy and a higher quality of life. For
athletes, it can enhance recovery following a strenuous exercise bout.
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The following
documents in PDF format. To be able to
read them you must have Adobe Reader installed on your
computer. To download Adobe Reader click the logo. |
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Bioenergy has prepared a
white paper on the effect of Bioenergy RIBOSE in ischemic, hypoxic, and
failing hearts, or you can refer to a complete list of references
below for more information.
- Orly Carter, Dean
MacCarter, Steve Mannebach, Joseph Biskupiak, Greg Stoddard,
Edward M. Gilbert, Mark A. Munger, D-Ribose Supplementation
Improves Peak Exercise Capacity And Ventilatory Efficiency In
Heart Failure Patients JACC 2005;45(3 Suppl A):185A -
Abstract (PDF)
- Daniel F. Pauly MD
PhD, and Carl J. Lepine MD D-Ribose As A Supplementation For
Cardiac Energy Metabolism J Card Parm Ther
5(4):249-258, 2000 -
Full Paper (PDF)
- Daniel F. Pauly MD
PhD, C Johnson, J A St.Cyr, The Benefits Of Ribose In
Cardiovascular Disease Med Hypoth (2003) 60(2),
149-151 -
Full Paper (PDF)
- Heyder Omran,
Steffan Illien, Dean MacCarter, J. St.Cyr, Berndt Luderitz,
D-Ribose Improves Diastolic Function And Quality Of Life In
Congestive Heart Failure Patients: A Prospective Feasibility
Study Eur Jour Hrt Fail 2003;5 615-619 -
Full Paper (PDF)
- D. Perkowski, S.
Wagner, A. Marcus, J. St.Cyr, D-Ribose And "Off" Pump
Coronary Artery Bypass Aids In Cardiac Indices Following
Myocardial Infarction Abstract Presentation July
16-21, 2005 -
Abstract (PDF)
- D. Perkowski, S.
Wagner, A. Marcus, J. St.Cyr, Ribose Enhances Ventricular
Function Following Off Pump Coronary Artery Bypass Surgery
Abstract Presentation January 7-9, 2005 -
Abstract (PDF)
- D. Perkowski, S.
Wagner, A. Marcus, J. St.Cyr, Pre-Surgical Loading Of Oral
D-Ribose Improves Cardiac Index In Patients Undergoing "Off"
Pump Coronary Artery Revascularization FASEB J (Part
1) 2005; 19(4): A695 -
Abstract (PDF)
- Wolfgang Pliml,
Thomas Von Arnim, Alexander Stablein, Hubert Hofmann, Heinz-Gerd
Zimmer, Erland Erdmann, Effects Of Ribose On Exercise-Induced
Ischemia In Stable Coronary Artery Disease The Lancet
340(8818): 507-510 -
Full Paper (PDF)
- Ram Sharma, Mark
Munger, Sheldon Litwin, Orly Vardeny, Dean MacCarter, John
St.Cyr, D-Ribose Improves Dopples Tei Myocardial Performance
Index And Maximal Exercise Capacity In Stage C Heart Failure
JMCC 38(5): 853, 2005 -
Abstract (PDF)
- Nampalli Vijay,
Dean MacCarter, Melinda Washam, Mark Munger, John St.Cyr,
D-Ribose Improves Ventilatory Efficiency In Congestive Heart
Failure Patients (NYHA Classes II-IV) Abstract
Presentation September 18-21, 2005 -
Abstract (PDF)
- Nampalli Vijay,
Dean MacCarter, Melinda Washam, John St.Cyr, Ventilatory
Efficiency Improves With D-Ribose In Congestive Heart Failure
Patients JMCC 38(5): 820, 2005 -
Abstract (PDF)
- W Wallen, M
Belanger, C Wittnich, Preischemic Administration Of Ribose To
Delay The Onset Of Irreversible Ischemic Injury And Improve
Function: Studies In Normal And Hypertrophied Hearts Can.
J. Physiol. Pharmacol. 81: 40-47 (2003) -
Full Paper (PDF)
- R Wilson, D.
MacCarter, J St.Cyr, D-Ribose Enhances The Identification Of
Hibernating Myocardium Heart Drug 3:61-62, 2003 -
Full Paper (PDF)
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