Bioenergy Ribose - Patented Structure and Function Claims

Energy Claims

• Ribose speeds energy recovery.
• Ribose increases energy reserves.
• Ribose builds ATP in heart and muscle.
• Ribose maintains healthy energy levels in heart and muscle.

References:
1. Pauly DF, CJ Pepine. D-ribose as a supplement for cardiac energy metabolism. J Cardiovasc Pharmacol Therapeut, 5(4):249-258, 2000.
2. Wagner DR, U Gresser, N Zollner. Effects of oral ribose on muscle metabolism during bicycle ergometer in AMPD-deficient patients. Ann Nutr Metab, 35:297-302, 1991.
3. Zarzeczny R, JJ Brault, KA Abraham, CR Hancock, RL Terjung. Influence of ribose on adenine salvage after intense muscle contractions. J Appl Physiol, 91:1775-1781, 2001.
4. Brault JJ, RL Terjung. Purine salvage to adenine nucleotides in different skeletal muscle fiber types. J Appl Physiol, 91:231-238, 2001.
5. Gallagher PM, DL Williamson, MP Godard, J Witter, SW Trappe. Effects of ribose supplementation on adenine nucleotide concentration in skeletal muscle following high-intensity exercise. Med Sci Sport Exc, 33(5 suppl), 2001.
6. Skadhauge-Jensen L, J Bangsbo, Y Hellsten. Availability of ribose is limiting for ATP reynsthesis in human skeletal muscle after high-intensity training. Med Sci Sport Exc, 33(5 suppl), 2001.
7. Wagner DR, N Zollner. McArdle’s disease: Successful symptomatic therapy by high dose oral administration of ribose. Klin Wochenschr 69:92, 1991.
8. Zollner N, S Reiter, M Gross, D Pongratz, CD Reimers, K Gerbitz, I Paetzke, T Deufel, G Hubner. Myoadenylate deaminase deficiency: Successful symptomatic therapy by high dose oral administration of ribose. Klin Wochenschr 64:1281-1290, 1986.
9. Patten BM. Beneficial effect of D-ribose in patient with myoadenylate deaminase deficiency. The Lancet, May:1071, 1982.


Cramping and Soreness Claims

Ribose relieves post-exertional muscle cramping and soreness.


References:
1. Wagner DR, N Zollner. McArdle’s disease: Successful symptomatic therapy by high dose oral administration of ribose. Klin Wochenschr 69:92, 1991.
2. Zollner N, S Reiter, M Gross, D Pongratz, CD Reimers, K Gerbitz, I Paetzke, T Deufel, G Hubner. Myoadenylate deaminase deficiency: Successful symptomatic therapy by high dose oral administration of ribose. Klin Wochenschr 64:1281-1290, 1986.
3. Wagner DR, U Gresser, N Zollner. Effects of oral ribose on muscle metabolism during bicycle ergometer in AMPD-deficient patients. Ann Nutr Metab, 35:297-302, 1991.


Heart and Quality of Life Claims

• Quality of life is enhanced by taking ribose.
• Ribose increases tolerance to cardiac stress.
• Ribose improves exercise tolerance and physical function.
• Ribose provides healthy levels of cardiac energy needed to maintain normal heart function.

References:
1. Omran H, S Illien. Ribose improves myocardial function and quality of life in congestive heart failure patients. J Mol Cell Cardiol, 33(6):A173, 2001.
2. Pauly DF, CJ Pepine. D-ribose as a supplement for cardiac energy metabolism. J Cardiovasc Pharmacol Therapeut, 5(4):249-258, 2000.
3. Illien S, H Omran, D MacCarter, JA St. Cyr. Ribose improves myocardial function in congestive heart failure. FASEB J, 15(5):A1142, 2001.
4. Pliml W, T von Arnim, A Stablein, H Hofmann, H-G Zimmer, E Erdmann. Effects of ribose on exercise-induced ischemia in stable coronary artery disease. The Lancet, 340:507-510, 1992.
5. Grant GF, RW Gracy. Therapeutic nutraceutical treatments for osteoarthritis and ischemia. Exp Opin Ther Patents, 10(1):1-10, 2000.


Physical Performance Claims

• Ribose improves physical performance.
• Ribose increases athletic performance.

References:
1. Williamson DL, MP Goddard, SW Trappe. Effects of ribose supplementation on performance during repeated high-intensity cycle sprints. Med Sci Sport Exc, 33(5 suppl), 2001
2. Van Gammeren D, D Falk, J Antonio. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: A double-blind, placebo controlled trial. Cur Therapeut Res, 63(8):486-495. 2002.
3. Patten BM. Beneficial effect of D-ribose in patient with myoadenylate deaminase deficiency. The Lancet, May:1071, 1982.


Metabolic Stress Claims

• Ribose decreases free radical formation during exercise.
• Ribose increases the hypoxic threshold of tissue.
• Ribose increases cardiac efficiency and lowers stress during exercise.

References:
1. Seifert JG, A Subudhi, M-X Fu, KL Riska, JC John. The effects of ribose ingestion on indices of free radical production during hypoxic exercise. Free Rad Biol Med, 33(Suppl 1):S269, 2002.
2. Segal S, J Foley. The metabolism of D-ribose in man. J Clin Invest, 37: 719-735, 1958.
3. Bierman EL, EM Baker, IC Plough, WH Hall. Metabolism of D-ribose in diabetes mellitus. Diabetes, 8(6):455-458, 1959.
4. Steinberg T, RL Poucher, RK Sarin, RB Rees, G Gwinup. Oran administration of D-ribose in diabetes mellitus. Diabetes, 19(10):11-16, 1970.
5. Zimmer H-G, H Ibel. Ribose accelerates the repletion of the ATP pool during recovery from reversible ischemia of the rat myocardium. J Mol Cell Cardiol, 16:863-866, 1984.


 

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