Each Serving of 1 Softgel Provides:

Ingredient		Amount		US RDA
Calories		10
Calories from Fat		10 g
Total Fat		1 g		2%
Saturated Fat		0 g		0%*
Polyunsaturated Fat		1 g
Safflower Seed Oil (high linoleic acid)		1,000 mg		*
Conjugated Linoleic Acid (CLA)		840 mg		*
Oleic Acid		100 mg		*
Linoleic Acid		30 mg		*
Ingredients: Safflower Seed Oil, gelatin, glycerin, water, caramel (natural color). *Daily value not established.

Research Studies Proves CLA Burns Fat: Studies show that Tonalin CLA works three ways to help you achieve your diet goals. As a result, you get smaller in all the right places. You drop clothes sizes. You look great. You feel great. And no yo-yo dieting effect.

Dietary CLA has been shown to effect body composition by creating a reduction in body fat and an enhancement of lean tissue or muscle. According to Michael Pariza at the University of Wisconsin, this area of CLA research is the most supported. Recently, the research has focused on clinical studies with much success; showing statistically significant reduction in body fat as measured by BMI (Body Mass Index). A significant decrease measured in waistline measured in inches, a positive result for weight loss in mildly overweight subjects and an increase in strength. Human clinical studies to substantiate improved body composition have been conducted worldwide. Positive results of CLA supplementation have been seen at research centers worldwide.

(Kent State University, University of Memphis, University of Wisconsin, USDA Western Human Research Center, Medstat Research Ltd. in Norway, Uppsala University in Sweden, University of Kumanoto in Japan and University of Tours in France).

CLA appears to exert direct effects on adipocytes, which are the principle sites of fat storage and skeletal muscle cells and are the primary sites of fat combustion. It has been proposed that the physiologic mechanism of body fat reduction by CLA involves inhibition of fat storage in adipocytes coupled with elevated b-oxidation in skeletal muscle. An overall increase in skeletal muscle tissue may be mediated at least in part via the inhibition of immune-induced catabolism.

CLA is a metabolically active compound that has been demonstrated to dramatically reduce body fat and increase lean body tissue. The mechanisms of action are not completely understood, but because CLA has been shown to affect a wide variety of enzymes and hormones in the body, multiple mechanisms may come into play. Numerous human studies are in progress, which will make a stronger case for efficacy and dose response. Expectations are high that research will additionally show no regain of body fat lost, suggesting that Tonalin? CLA should be included with every diet regimen.

Not only does Tonalin® have no harmful side effects, but it's actually good for your body. As a matter of fact, scientists worldwide are just beginning to understand CLA's wide range of potential health benefits. Here are quick summaries of CLA's current four principal health benefit areas.

CLA for Cancer: In the early 1980s, Dr. Michael Pariza, working at the University of Wisconsin discovered that CLA interfered with the growth of cancer tumors. Since then, a number of other studies have further shown CLA's cancer-fighting potential. Some of these studies have shown that CLA can suppress cancer development in animals, and in human cancer cell lines in vitro. Dietary CLA also seems to protective against breast cancer in humans, as demonstrated in a large study at the University Francois-Rabelais. When breast adipose tissue was collected at the time of surgery, higher levels of CLA in the control group suggested CLA's protective effect against breast cancer. A different study in Finland confirmed the reverse correlation between milk fat intake, which contains CLA and breast cancer. Over the next few years, additional studies are planned to help further understand the role CLA may play in the fight against cancer.

A Natural Ingredient for Diabetics: One of the most important health benefits of CLA could possibly be its ability to affect and treat some types of diabetes. According to Dr. Martha Belury at Purdue University and Dr. John Vandel Heuvel at Penn State University, CLA normalizes impaired glucose tolerance in non insulin-dependent diabetes. In earlier experiments it was observed that CLA and troglitazone reversed the symptoms of diabetes in a specific diabetic animal model. Effects included decreased triglycerides, insulin and leptin, and improved glucose utilization. CLA may represent an important agent for the treatment of Type II diabetes. Because CLA isomers share many of the attributes of troglitazone, without exhibiting as many side effects, CLA may represent a new insulin-sensitizing agent for treatment of Type II diabetes. Additional clinical studies are scheduled at many universities worldwide in order to further explore the possibilities of using CLA for diabetes treatment.