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NutraBio.com Amino Therapy Amino Acids

Arginine Pyroglutamate & Lysine

Proven Natural Growth Hormone (GH) Releaser.

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Arginine stimulates the natural release of growth hormone and is a far safer and more cost effective alternative to growth hormone treatment such as HGH injections. Growth hormone is one of the most powerful hormones in the human body which promotes the growth of lean muscle tissue and the loss of fat. As you age, growth hormone levels drop, which is one reason you lose muscle and gain fat. In a controlled trial, when arginine and other amino acids were combined with weight training, a greater decrease in body fat was obtained after only five weeks than when the same exercise was combined with a placebo. Arginine is also needed to increase protein synthesis, which can in turn increase muscle growth.

Advanced absorption & delivery. 100% pure pharmaceutical grade with no fillers or additives.
Click here for all arginine powders and capsules.

Powder 150 Grams Item #24540 $14.89 save 55%
500 Grams Item #24541 $34.99 save 65%
1,000 Grams * Item #24542 $54.99 save 75%
2,500 Grams * Item #24543 $123.72 save 78%
600 mg
Capsules
150 Caps Item #24546 $13.50 save 60%
500 Caps Item #24547 $39.96 save 68%
1,000 Caps * Item #24548 $64.98 save 75%
2,000 Caps * Item #24549 $114.36 save 76%
* Freshness Guarantee: To maintain product freshness we ship this product in multiples of 500 Gram or 500 Capsule bottles. For example if you order 1000 Grams you'll receive 2 bottles of 500 Grams each. Use the first bottle while the second stays sealed and fresh.

This product is Hypoallergenic - Pharmaceutical Grade. Vegetarian in powder form only.

Arginine Pyroglutamate & Lysine Improve Growth Hormone (GH) levels:  Arginine stimulates the natural release of growth hormone and is a far safer and more cost effective alternative to growth hormone treatment such as HGH injections. Growth hormone is one of the most powerful hormones in the human body which promotes the growth of lean muscle tissue and the loss of fat. As you age, growth hormone levels drop, which is one reason you lose muscle and gain fat. In a controlled trial, when arginine and other amino acids were combined with weight training, a greater decrease in body fat was obtained after only five weeks than when the same exercise was combined with a placebo. Arginine is also needed to increase protein synthesis, which can in turn increase muscle growth. [1,2]

L-arginine taken on an empty stomach can cause a significant release of growth hormone in many people. A dosage of between 10 and 30 grams of L-Arginine, depending upon factors such as age and body weight, is needed to have any impact on GH release. Taking arginine in capsule form is not recommended because it would take upwards of 20 capsules per serving to have a substantial impact on GH, which is why powder is the recommended delivery method. However, research shows that when arginine pyroglutamate is combined with lysine the dosage of arginine drops dramatically. Just 1200mg of each nightly has been shown to substantially increase GH.

Growth Hormone (GH) for the athlete:Athletes involved in intense exercise on a regular basis need Growth Hormone (GH) to increase energy, enhance lean body mass and to maintain strong bones and keep their weight under control. Availability of GH in systemic circulation also helps increase strength, burn fat, enhance libido, boost immunity and support tendons and ligaments. By inducing the secretion of GH from the pituitary, arginine and lysine stimulate muscle metabolism and, hence, provide nutritional support for the athlete. 

Research shows Arginine Pyroglutamate and L-Lysine may improve GH levels: The combination of Arginine Pyroglutamate with L-lysine is one of the first natural GH releasers proven by scientific research to work. L-Arginine L-Pyroglutamate was the focus of world-wide attention in 1981 when Italian researcher A. Isidori, M.D., and his colleagues of the University of Rome determined that a combination of L-Lysine and L-Arginine L-Pyroglutamate when given orally to a group of 15 male volunteers between the ages of 15 and 20 was more than 10 times more effective at increasing blood levels of human growth hormone than taking only the amino acid L-Arginine by itself (yielding a average net GH increase of more than 700%). According to these researchers, "we could demonstrate that the association of the two amino acids does result in the release of biologically active GH able to affect peripheral cellular receptors and thus cell growth in general."[3].

One reason this combination might be so effective is that free form "L" versions of Lysine and Arginine compete for the same receptors. Replacing L-arginine with Arginine Pyroglutamate prevents competition for the same receptors. It is suggested that Arginine Pyroglutamate attaches to a different receptor allowing for a synergistic effect between the two amino acids. NutraBio's Arginine Pyroglutamate Plus Lysine combines 1200 mg of L-Arginine L-Pyroglutamate along with 1200 mg of free form L-Lysine which is the exact formula used in the university study that proved the most beneficial combination to promote GH levels.

Which Arginine should I take to boost Growth Hormone (GH) and Nitric Oxide?  If you are taking arginine with the sole purpose of releasing growth hormone, the best alternative would be our Arginine Pyroglutamate Plus Lysine which is specifically designed and proven for this purpose and requires a much smaller dose of only 2.4 grams as opposed to 10 to 30 of L-Arginine. This smaller dose however will not be sufficient for nitric oxide release, nutrient delivery enhancement or sexual performance. If you are looking for both Growth Hormone and Nitric Oxide release than a good methodology would stacking multiple types of Arginine. Take 1-2 doses of Arginine Ethyl Ester (AEE) or Arginine Alpha Ketoglutarate (AAKG) earlier in the day and before workouts, and take one dose of Arginine Pyroglutamate and Lysine at night time. This stack gives you the most effective method for increasing nitric oxide to give you an ultimate muscle pump while improving GH levels for muscle growth. If taking two doses of AAKG or AEE earlier in the day make sure to separate both doses and the nighttime Arginine Pyroglutamate Plus Lysine by at least 3 hours. If you miss any of the doses, do not double up on the next dose just continue on with your next dose as normal.

Overall benefits of Arginine Supplementation:

  • Supports protein synthesis.
  • Increases blood flow to muscle tissue.
  • Boosts circulatory health.
  • Increases level of nitric oxide.
  • Promotes healthy sexual function.
  • Improves nutrient delivery.
  • Increases levels Growth Hormone (GH).
  • Promotes healing. Helps remove waste from body.

Click here to view all arginine products.   

NutraBio.com Amino Therapy Amino Acids

We guarantee our supplements to be the freshest and purest: Our powders and capsules contain only pure active ingredient with absolutely no fillers. Other manufacturers, in an effort to keep costs down, dilute their products with cheap fillers like maltodextrin and dextrose. These practices cheat you out of the active ingredient. Many popular body building products can contain over 50% maltodextrin. This product contains no additives or excipients other than minor amount of silica to prevent the powder from hardening. NutraBio supplements are manufactured under the strictest standards producing the highest quality and purest supplements available anywhere. Our raw ingredients undergo state of the art HPLC analysis to insure zero tolerance for impurities and we ship our products direct which guarantees the freshness and gives you a minimum of 30 months before expiration.

Expiration 30 months minimum
Grade pharmaceutical
Purity 99.9%+ purity (HPLC)
Taste n/a
Solubility water soluble/mixes well
Characteristics Hypoallergenic. Vegetarian in power form, gelatin capsule is not. Not kosher
Appearance white crystalline powder
Odor n/a
pH n/a
Classification (blended amino acid): sports & muscle building, blood & nutrient delivery, Nitric Oxide, Growth Hormone, sexual enhancement.
CAS Registry 56265-06-6 & 657-27-2 blend 1:1
Synonyms Arginine Pyroglutamate & L-Lysine
Molecular Formula C6H14N4O2C5H7NO3 & C6H14N2O2|HCl
Molecular structure

n/a

Manufactured from L-Arginine bonded to Pyroglutamate, in a blend with L-Lysine

Arginine Pyroglutamate with L-Lysine powderRecommended Use: As a dietary supplement, take one serving at night and preferably on an empty stomach.  The effectiveness of arginine for growth hormone release is age-dependent. A person in their twenties can get a very high release of growth hormone whereas a person in their fifties would get a lower response.

For best results for growth hormone (GH) release:The effectiveness of arginine in releasing growth hormone is greatly diminished if foods have been consumed that cause other amino acids or significant amounts of insulin to be present in the bloodstream along with the arginine. That is why arginine should be taken on an empty stomach at least one hour before or three hours after a meal.  For the purpose of increasing growth hormone, Arginine Pyroglutamate with L-Lysine capsulesArginine supplements are best taken before bedtime to maximize its beneficial effects and to allow GH secretion to synchronize with the body's own rhythm of GH production.

Hypoallergenic:Contains no yeast, dairy, egg, gluten, corn, soy, wheat, sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN. If you are pregnant or breast feeding, consult your health care professional before using this product. People with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking any dietary supplements. Do not use if you are at risk or are being treated for high blood pressure, liver, thyroid, psychiatric disease, diabetes or hypoglycemia. Do not use if you have had a myocardial infraction (heart attack). This supplement should be used by healthy adults only. Do not use unless you have obtained proper clearance from your healthcare professional. 



NutraBio Pure
An unprecedented commitment to
quality, purity and freshness since 1996!

We manufacture in our own FDA registered and inspected GMP facility:

Since 1996, NutraBio has manufactured the purest pharmaceutical grade products available. We manufacture in the United States in our own FDA registered and inspected facility to meet FDA 21 CFR Part 111 cGMP regulations. All ingredients undergo state-of-the-art analysis to insure zero tolerance for impurities.

Truthful and Clear Supplement Facts Panels - No BS Proprietary Blends:

A proprietary blend is a cheap gimmick used by manufacturers to hide the real truth about what's in their product. By listing a bunch of ingredients under one blend on the label, the manufacturer only has to tell you how much of the blend is in a serving while hiding how much of each ingredient is in a serving. They pretend to this to protect their secret formula, that’s bull, they do it so they can cheapen their product without their customers knowing. In the industry we call this “Window Dressing” the product the label looks good on the outside but there is nothing really happening on the inside. At NutraBio our Supplement Facts panels list the exact amount of each and every active ingredient in the supplement. No guessing, you know exactly what you are getting in every product we sell.

Purchase manufacturer direct at wholesale price:

Buy directly from the manufacturer and save. We cut out the middlemen and pass the savings on to you. With NutraBio, you pay the same low wholesale price that the chain stores pay. Did you know that most companies do not manufacture their products but use 3rd party manufacturers? Since we manufacture all of our own products we can control the quality and purity through the entire manufacturing process. We never sell old or near expired products.

v-20110711
rev-20111011

1. Rudman D, Feller AG, Nagraj HS, Gergans GA, Lalitha PY, Goldberg AF, Schlenker RA, Cohn L, Rudman IW, Mattson DE. (1990). Effects of human growth hormone in men over 60 years old. New England Journal of Medicine, 323, 1-6 .  2. Elam, R.P. (1988). Morphological changes in adult males from resistance exercise and amino acid supplementation. Journal of Sports Medicine and Physical Fitness, 28, 35-39 .  3. http://www.ncbi.nlm.nih.gov/pubmed/6790230?dopt=Abstract  

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