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L-Arginine (AjiPure - free form)

AjiPure Pharmaceutical 99.98% pure with no fillers or additives.

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Our free-form L-Arginine is Ajinomoto pharmaceutical grade HPLC verified ultra-pure for maximum bioavailability and effectiveness. Arginine (or L-Arginine) is a crystalline free-form amino acid involved in numerous areas of human biochemistry, including muscle metabolism, hormone secretion, ammonia detoxification, and the immune system. Arginine promotes nitric oxide production, which helps support circulation and muscles.

  • Supports protein synthesis.
  • Increases blood flow to muscle tissue.
  • Boosts circulatory health.
  • Increases level of nitric oxide.
  • Promotes healthy sexual function.
  • Improves nutrient delivery.
  • May increase levels Growth Hormone (GH).
  • Promotes healing & helps remove waste.

We have 9 arginine formulas available.

New! Now 50% higher potency vegetable capsules.
AjiPure the purest Pharmaceutical Arginine available.

Powder

NutraBio OU kosher Kosher
150 Grams Item #23330 $9.43 save 55%
500 Grams Item #23331 $25.94 save 65%
1,000 Grams * Item #23332 $45.86 save 72%
2,500 Grams * Item #23333 $103.18 save 81%
750 mg
Vegetable Capsules

NutraBio OU kosher Kosher
150 V-Caps Item #23336 $14.35 save 60%
500 V-Caps Item #23337 $40.65 save 68%
1,000 V-Caps * Item #23338 $71.55 save 75%
2,000 V-Caps * Item #23339 $125.94 save 76%
* Freshness Guarantee: To maintain product freshness we ship this product in multiples of 500 Gram or 500 Capsule bottles. For example if you order 1000 Grams you'll receive 2 bottles of 500 Grams each. Use the first bottle while the second stays sealed and fresh.

This product is Kosher Pareve - Vegetarian - Hypoallergenic - Pharmaceutical Grade.
Click here to view certification.

Arginine promotes increased nitric oxide (NO) production for enhanced blood flow and better delivery of oxygen and nutrients to working muscle.

L-Arginine is one of 20 amino acids, the building blocks of protein. Arginine can serve as a source of energy, and is involved in various pathways throughout the body. Arginine supports the effect of exercise and is one of the most important amino acids involved in immune function.L-Arginine is considered a semi-essential amino acid, because although it is normally synthesized in sufficient amounts by the body, supplementation is sometimes required. Arginine supports protein synthesis as it is involved in the transport and storage of nitrogen and is important for proper physical performance because it is used by the body to produce creatine.

L-Arginine is required for the synthesis of nitric oxide, a secondary messenger involved in blood flow. Nitric oxide is a compound that helps keep blood vessels dilated to promote healthy blood flow. Arginine also stimulates protein synthesis and has been studied for wound healing, bodybuilding, enhancement of sperm production (spermatogenesis), and prevention of wasting in people with critical illness. L-Arginine is beneficial for overall cardiovascular maintenance and sexual function as well as other areas that depend largely on healthy circulatory status.

  • Supports protein synthesis.
  • Increases Nitric Oxide.
  • Increases blood flow to muscle tissue.
  • Boosts circulatory health.
  • Promotes healthy sexual function.
  • Improves nutrient delivery.
  • Increases levels Growth Hormone (GH).
  • Promotes healing. Helps remove waste from body.

L-Arginine was first isolated in 1886. In 1932, L-Arginine was found to be required for the generation of urea, which is necessary for the removal of toxic ammonia from the body. In 1939, L-Arginine was also shown to be required for the synthesis of creatine. Creatine degrades to creatinine at a constant rate, and is cleared from the body by the kidney. Arginine is also a precursor of guanido-phosphate, phosphor-arginine and creatine, the high-energy compounds found in muscles. L-Arginine has been used extensively by bodybuilders to increase blood flow to muscle tissue and to enhance creatine storage in the body although recently Arginine Alpha-ketoglutarate has become more popular. Arginine is also an important factor in muscle metabolism and works to transport, store and excrete nitrogen. Free form L-Arginine has a bitter and pretty bad taste in a pure powder form.

Arginine Improves Growth Hormone (GH) levels:

Arginine stimulates the natural release of growth hormone and is a far safer and more cost effective alternative to growth hormone treatment such as HGH injections. Growth hormone is one of the most powerful hormones in the human body which promotes the growth of lean muscle tissue and the loss of fat. As you age, growth hormone levels drop, which is one reason you lose muscle and gain fat. In a controlled trial, when arginine and other amino acids were combined with weight training, a greater decrease in body fat was obtained after only five weeks than when the same exercise was combined with a placebo. Arginine is also needed to increase protein synthesis, which can in turn increase muscle growth. [1,2].

L-Arginine taken on an empty stomach can cause a significant release of growth hormone in many people. A dosage of between 10 and 30 grams of L-Arginine, depending upon factors such as age and body weight, is needed to have any impact on GH release. Taking arginine in capsule form is not recommended because it would take upwards of 20 capsules per serving to have a substantial impact on GH, which is why powder is the recommended delivery method. Growth hormone releasers should not be used by children until five years after they have completed their long bone growth (unless under careful medical supervision). The effectiveness of arginine for growth hormone release is age-dependent. A person in their twenties can get a very high release of growth hormone whereas a person in their fifties would get a lower response.

Growth Hormone (GH) for the athlete:

Athletes involved in intense exercise on a regular basis need Growth Hormone (GH) to increase energy, enhance lean body mass and to maintain strong bones and keep their weight under control. Availability of GH in systemic circulation also helps increase strength, burn fat, enhance libido, boost immunity and support tendons and ligaments. By inducing the secretion of GH from the pituitary, arginine and lysine stimulate muscle metabolism and, hence, provide nutritional support for the athlete. 

The combination of L-Arginine L-Pyroglutamate and L-Lysine may improve GH Levels:

The combination of Arginine Pyroglutamate with L-lysine is one of the first natural GH releasers proven by scientific research to work. L-Arginine L-Pyroglutamate was the focus of world-wide attention in 1981 when Italian researcher A. Isidori, M.D., and his colleagues of the University of Rome determined that a combination of L-Lysine and L-Arginine L-Pyroglutamate when given orally to a group of 15 male volunteers between the ages of 15 and 20 was more than 10 times more effective at increasing blood levels of human growth hormone than taking only the amino acid L-Arginine by itself (yielding a average net GH increase of more than 700%). According to these researchers, "we could demonstrate that the association of the two amino acids does result in the release of biologically active GH able to affect peripheral cellular receptors and thus cell growth in general."[3].

One reason this combination might be so effective is that free form "L" versions of Lysine and Arginine compete for the same receptors. Replacing L-Arginine with Arginine Pyroglutamate prevents competition for the same receptors. It is suggested that Arginine Pyroglutamate attaches to a different receptor allowing for a synergistic effect between the two amino acids. NutraBio's Arginine Pyroglutamate Plus Lysine combines 1200 mg of L-Arginine L-Pyroglutamate along with 1200 mg of free form L-Lysine which is the exact formula used in the university study that proved the most beneficial combination to promote GH levels.

Which Arginine should I take to boost Growth Hormone (GH) and Nitric Oxide?

If you are taking arginine with the sole purpose of releasing growth hormone, the best alternative would be our Arginine Pyroglutamate Plus Lysine which is specifically designed and proven for this purpose and requires a much smaller dose of only 2.4 grams as opposed to 10 to 30 of L-Arginine. This smaller dose however will not be sufficient for nitric oxide release, nutrient delivery enhancement or sexual performance. If you are looking for both Growth Hormone and Nitric Oxide release than a good methodology would stacking multiple types of Arginine. Take 1-2 doses of Arginine Ethyl Ester (AEE) or Arginine Alpha Ketoglutarate (AAKG) earlier in the day and before workouts, and take one dose of Arginine Pyroglutamate and Lysine at night time. This stack gives you the most effective method for increasing nitric oxide to give you an ultimate muscle pump while improving GH levels for muscle growth. If taking two doses of AAKG or AEE earlier in the day make sure to separate both doses and the nighttime Arginine Pyroglutamate Plus Lysine by at least 3 hours. If you miss any of the doses, do not double up on the next dose just continue on with your next dose as normal.

Other Arginine Supplements:

NutraBio offers many types of Arginine supplements, stacks and derivatives to suit your individual needs. Click here to view all arginine products. 

We guarantee our supplements to be the freshest and purest: Our powders and capsules contain only pure active ingredient with absolutely no additives. Other manufacturers, in an effort to keep costs down, dilute their products with cheap fillers and add chemical excipients to their products to speed up their manufacturing output. These practices cheat you out of the active ingredient. At NutraBio, we've perfected our manufacturing technology so that excipients aren't needed, that means no microcrystalline cellulose, magnesium stearate, silica or other fillers, just 100% pure active ingredient. NutraBio supplements are manufactured under the strictest standards producing the highest quality and purest supplements available anywhere. Our raw ingredients undergo state of the art HPLC analysis to insure zero tolerance for impurities and we manufacture our products every 2 weeks which guarantees you a minimum of 34 months before expiration.

 

Expiration 30 months minimum
Grade pharmaceutical
Purity 99.9%+ purity (HPLC)
Taste powder is bitter and bad tasting
Solubility water soluble
Characteristics Hypoallergenic. Powder only is kosher and vegetarian because capsule is made from gelatin.
Appearance white crystalline powder
Odor n/a
pH ≈1.8
Classification (Amino Acid): sports & muscle building, blood & nutrient delivery, Nitric Oxide, Growth Hormone, sexual enhancement.
CAS Registry 74-79-3
Synonyms L-Arginine Base. 2-Amino-5-guanidinovaleric acid,
2-Amino-5-guanidinopentanoic acid
Molecular Formula C6H14N4O2
Molecular structure

Manufactured from pure L-Arginine, plant based

Amino acids    Arginine & Arginine Derivatives


Suggested Usage:

As a dietary supplement take 1 level scoop (1500 mg) of powder or 2 capsules with water or your favorite beverage,  1-2 times daily or as directed by your physician. For maximum benefit, take up to 3 grams (3000mg) per day.  When using powder mix for 15 to 20 seconds using a shaker cup or mix thoroughly with a spoon. May not mix very easily. May be hygroscopic and may clump during storage. This does not effect the efficacy of the product, but just the texture. Can be mixed with your creatine supplements for enhanced results. Free form L-Arginine has a bitter and pretty bad taste in the powder form so capsules are recommended. Arginine is available in many other forms. Click here to view additional arginine supplement and derivatives.

For best results for growth hormone (GH) release:

The effectiveness of arginine in releasing growth hormone is greatly diminished if foods have been consumed that cause other amino acids or significant amounts of insulin to be present in the bloodstream along with the arginine. That is why arginine should be taken on an empty stomach at least one hour before or two hours after a meal.  For the purpose of increasing growth hormone, Arginine supplements are best taken before bedtime to maximize its beneficial effects and to allow GH secretion to synchronize with the body's own rhythm of GH production.

Hypoallergenic:

Contains no yeast, dairy, egg, gluten, corn, soy, wheat, shellfish, sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Suitable for vegetarians:

Our L-Arginine is suitable for vegetarians however the gelatin capsule is not.

Warning:

NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN. If you are pregnant or breast feeding, consult your health care professional before using this product. People with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking any dietary supplements. Do not use if you are at risk or are being treated for high blood pressure, liver, thyroid, psychiatric disease, diabetes or hypoglycemia. Do not use if you have had a myocardial infraction (heart attack). This supplement should be used by healthy adults only. Do not use unless you have obtained proper clearance from your healthcare professional. 



NutraBio Pure
An unprecedented commitment to
quality, purity and freshness since 1996!

We manufacture in our own FDA registered and inspected GMP facility:

Since 1996, NutraBio has manufactured the purest pharmaceutical grade products available. We manufacture in the United States in our own FDA registered and inspected facility to meet FDA 21 CFR Part 111 cGMP regulations. All ingredients undergo state-of-the-art analysis to insure zero tolerance for impurities.

Truthful and Clear Supplement Facts Panels - No BS Proprietary Blends:

A proprietary blend is a cheap gimmick used by manufacturers to hide the real truth about what's in their product. By listing a bunch of ingredients under one blend on the label, the manufacturer only has to tell you how much of the blend is in a serving while hiding how much of each ingredient is in a serving. They pretend to this to protect their secret formula, that’s bull, they do it so they can cheapen their product without their customers knowing. In the industry we call this “Window Dressing” the product the label looks good on the outside but there is nothing really happening on the inside. At NutraBio our Supplement Facts panels list the exact amount of each and every active ingredient in the supplement. No guessing, you know exactly what you are getting in every product we sell.

Purchase manufacturer direct at wholesale price:

Buy directly from the manufacturer and save. We cut out the middlemen and pass the savings on to you. With NutraBio, you pay the same low wholesale price that the chain stores pay. Did you know that most companies do not manufacture their products but use 3rd party manufacturers? Since we manufacture all of our own products we can control the quality and purity through the entire manufacturing process. We never sell old or near expired products.

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1. Rudman D, Feller AG, Nagraj HS, Gergans GA, Lalitha PY, Goldberg AF, Schlenker RA, Cohn L, Rudman IW, Mattson DE. (1990). Effects of human growth hormone in men over 60 years old. New England Journal of Medicine, 323, 1-6 . 2. Elam, R.P. (1988). Morphological changes in adult males from resistance exercise and amino acid supplementation. Journal of Sports Medicine and Physical Fitness, 28, 35-39 . 3. http://www.ncbi.nlm.nih.gov/pubmed/6790230?dopt=Abstract


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