Vinpocetine
Main Function:
Improves brain metabolism by increasing oxygen flow to
the brain. Vinpocetine improve memory and mental energy. May improve overall
cognitive function, especially memory, concentration, and mental energy.
Improves circulation, oxygenation of the blood, and energy utilization in the
brain. Also improves vision.
Pronunciation:
vinn-PO-seh-teen

Vinpocetine is derived from an alkaloid found in the
periwinkle plant. Is has become popular as a memory enhancer and cognitive
aid and is used to treat a variety of neurological disorders, including; cerebrovascular disorders – low cerebral blood flow, headache, hypoxia,
cerebral atherosclerosis and stroke; mental impairment – poor memory,
aphasia, motor disorders, senility and dementias; sensory
disorders – hearing impairment, inner-ear problems,
dizziness, low visual acuity and diabetic retinopathy; failing neuronal
metabolism. Most of these uses have clinical and laboratory support.
Vinpocetine causes dilation of brain blood vessels and it
inhibits blood clotting. These actions improve cerebral blood flow, which might
explain many of the neurological benefits.
In addition, vinpocetine is thought to increase the
absorption of glucose by nerve cells, thereby providing extra energy for the
brain. These physiological processes are just beginning to be explored at the
molecular level. The fact vinpocetine improves memory and cognition in ailing
individuals has led many perfectly healthy people to conclude that it should
help them, too – an idea that makes a lot of sense.
Vinpocetine Is A Powerful Memory Enhancer
Vinpocetine is an oxygenator and activator of cerebral
metabolism and as a result it acts as a powerful memory enhancer.
Vinpocetine has been the focus of numerous studies conducted on healthy
volunteers to evaluate short and long term memory improvements. The studies
reflect how Vinpocetine can help develop and increase intelligence. Vinpocetine
has been shown to be particularly effective in functional symptoms such as
confusion, loss of attention, lack of concentration, irritability, vertigo,
visual and acoustic alterations, and mood changes. Vinpocetine has also been
shown to improve cognitive function, and clearly enhances mental lucidity and
memory levels.
Vinpocetine acts on both the circulatory system and the brains metabolism in the
following ways:
1. Vinpocetine passes through
the blood brain barrier and increases glucose
consumption
by brain cells. Glucose is the source of energy for brain cells.
2. Vinpocetine optimizes the
Krebs cycle and therefore helps achieve maximum
transformation of glucose into energy.
3. Vinpocetine increase levels of
oxygenation of the brain cells, and therefore
avoiding
hypoxias, which usually result in neuronal death.
4. Vinpocetine helps increase the
elasticity of erythrocytes, which eases the
microcirculation
through the brain capillaries and opens up the supply of
oxygen and glucose.
5. Vinpocetine works as a cerebral
vasodilator helping to improve cerebral
blood flow.
6. Vinpocetine may help inhibit platelet
aggregation. This function prevents
stroke as it stops
thromboses or blood clots from forming. In addition, the
increase elasticity of the
erythrocytes helps to reduce the impact that any
such clotting could have.
Vinpocetine is a derivative of natural plant extracts and has been used for many
years around the world, with proven degrees of efficiency as a powerful memory
enhancer.
Vinpocetine improves cerebral blood flow, decreases cerebral vascular resistance
and increases cerebral oxygen and glucose utilization. Vinpocetine inhibits
phosphodiesterase activity, prevents aggregation and adenosine intake by
erythrocytes. Vinpocetine may also suppress disturbances due to hypoxia or to
deficient cerebral metabolism.
Vinpocetine is a synthetic derivative of Vincamine and is thought to have a
higher degree of potency than Vincamine while exhibiting minimal side effects.
Classification: Oxygenator and Activator of Cerebral Metabolism
IUPAC Name: Eburnamenine-14-carboxylic acid ethylester.
Synonyms: Ethyl-apovincaminate, 3, 16 - apovincamininc acid-ethyl-ester
Product Category: Vasodilator and anti-ischemic
Suggested Dosage: 5 mg per day
Reported Uses:
Vinpocetine is reported to exhibit an activity on neuronal metabolism by
favoring the aerobic glycolysis and to promote the redistribution of the blood
flow towards ischemic areas. Vinpocetine may also act to increase cerebral
circulation and the utilization of oxygen, and is commonly cited as an aid to
improving memory.
Vinpocetine has been reported as showing promising results in the treatment of
tinnitus or ringing of the ears as well as other causes of impaired hearing.
Vinpocetine has also been indicated in the treatment of strokes, menopausal
symptoms and macular degeneration.
Vinpocetine may act to improve conditions related to insufficient blood flow to
the brain including vertigo and Menieres syndrome, difficulty in sleeping, mood
changes and depression.
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