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Huperzine-A

Main function: acetylcholine esterase inhibitor

Pronunciation:
hoo-PEHR-zeen


Huperzine is an alkaloid found in the club moss, Huperzia serrata – a plant used in Chinese traditional medicine. Huperzine is a potent inhibitor of the enzyme that disposes of acetylcholine in the brain; it therefore elevates acetylcholine levels. When taken orally, huperzine has shown a high bioavailability and rapid penetration into the brain. Side effects are minimal at therapeutic doses. Huperzine exhibits memory-enhancing activities in animals and humans. Its benefits are said to include increased alertness, greater short-term memory retention and increased energy.

Huperzine shows promise for treating Alzheimer’s disease and other dementias because:
  • It reduces oxidative damage produced by beta-ameloid protein (a protein overproduced in Alzheimer’s brains)
  • It elevates acetylcholine levels that are typically depleted by Alzheimer’s;
  • It has demonstrated ability to enhance memory;
  • It has a longer duration of action and higher therapeutic index than tacrine and donepezil (the best FDA-approved Alzheimer’s drugs).
Nutrabio.com Products Containing Huperzine A:  Neurogen+

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